CJC-1295 + Ipamorelin

Popular GHRH + ghrelin-mimetic pairing; rationale is physiological, but combination trials don't exist.

Unapproved / researchGrowth HormoneSleep

Not FDA-approved. Compounded; both components unapproved and WADA-prohibited. This page describes research and public discussion; it is not a recommendation to use.

Overview

Pairing a GHRH analogue with a GHS-R agonist can synergistically increase GH release in pharmacology studies of related compounds. The specific combination has not been clinically tested.

Mechanism of action

GHRH receptor stimulation (CJC) plus ghrelin-receptor stimulation (ipamorelin).

Benefits & evidence ratings

Synergistic GH releaseC Preliminary research
Better sleep, recovery, fat lossD Anecdotal / community

Dosing

Doses show what has been studied or discussed — not guidance. Always follow your prescriber.

SourceDoseFrequencyDurationRoute

Online protocols

D Anecdotal / community
~100 mcg eachNightly8–12 weeksSubcutaneous

Clinical trials & studies

No studies of this specific combination have been published.

Safety

Side effects

  • Flushing, water retention, hunger

Contraindications

  • Active cancer
  • Pregnancy

Interactions

  • Diabetes medication

Long-term safety

Unknown.

Regulatory status

Unapproved / research

Compounded; both components unapproved and WADA-prohibited.

FAQ

Commonly discussed alongside

Listing a combination does not mean it has been studied or is safe.