PT-141 + Oxytocin

Compounded intranasal combination of bremelanotide and oxytocin. The combination itself has not been studied.

Unapproved / researchSexual Wellness

Not FDA-approved. Compounded combination; not approved in any jurisdiction. This page describes research and public discussion; it is not a recommendation to use.

Overview

This blend pairs a melanocortin agonist with oxytocin. Each ingredient has its own evidence base (see component profiles), but no clinical trial has tested them together.

Mechanism of action

Combines MC4R-mediated desire signaling with oxytocin receptor activity.

Benefits & evidence ratings

Synergistic effect on desire and connectionD Anecdotal / community

Dosing

Doses show what has been studied or discussed — not guidance. Always follow your prescriber.

SourceDoseFrequencyDurationRoute

No studied combination dose

D Anecdotal / community
Varies by compounderAs needed—Intranasal

Clinical trials & studies

No studies of this specific combination have been published.

Safety

Side effects

  • Sum of component risks: nausea, flushing, BP elevation, headache

Contraindications

  • Uncontrolled hypertension
  • Pregnancy

Interactions

  • Naltrexone (with bremelanotide)

Long-term safety

Unknown.

Regulatory status

Unapproved / research

Compounded combination; not approved in any jurisdiction.

FAQ